Invention Grant
US09447449B2 Recombinant mycobacteriophages for delivery of nucleic acids of interest into mycobacteria
有权
用于将感兴趣的核酸递送至分枝杆菌的重组分枝杆菌噬菌体
- Patent Title: Recombinant mycobacteriophages for delivery of nucleic acids of interest into mycobacteria
- Patent Title (中): 用于将感兴趣的核酸递送至分枝杆菌的重组分枝杆菌噬菌体
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Application No.: US14352761Application Date: 2012-10-19
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Publication No.: US09447449B2Publication Date: 2016-09-20
- Inventor: William R. Jacobs , Graham F. Hatfull
- Applicant: Albert Einstein College of Medicine of Yeshiva University , University of Pittsburgh—Of the Commonwealth System of Higher Education
- Applicant Address: US NY Bronx US PA Pittsburgh
- Assignee: Albert Einstein College of Medicine, Inc.,University of Pittsburgh—of the Commonwealth System of Higher Education
- Current Assignee: Albert Einstein College of Medicine, Inc.,University of Pittsburgh—of the Commonwealth System of Higher Education
- Current Assignee Address: US NY Bronx US PA Pittsburgh
- Agency: Amster, Rothstein & Ebenstein LLP
- International Application: PCT/US2012/061059 WO 20121019
- International Announcement: WO2013/059616 WO 20130425
- Main IPC: C12N7/00
- IPC: C12N7/00 ; C12Q1/18 ; C12N15/74 ; C07K14/005
Abstract:
Methods are provided for detecting mycobacteria in a sample, including clinical samples. Methods are also provided for determining susceptibility of mycobacterial strains to known or potential antibiotic agents, as are kits therefor. Recombinant mycobacteriophages are also provided comprising heterologous nucleic acids of interest.
Public/Granted literature
- US20140370495A1 RECOMBINANT MYCOBACTERIOPHAGES FOR DELIVERY OF NUCLEIC ACIDS OF INTEREST INTO MYCOBACTERIA Public/Granted day:2014-12-18
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