Invention Grant
- Patent Title: Methods for concurrent identification and quantification of an unknown bioagent
- Patent Title (中): 同时鉴定和量化未知生物标签的方法
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Application No.: US14164559Application Date: 2014-01-27
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Publication No.: US09447462B2Publication Date: 2016-09-20
- Inventor: David J. Ecker , Rangarajan Sampath , Lawrence B. Blyn , Steven A. Hofstadler , Thomas A. Hall
- Applicant: Ibis Biosciences, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: IBIS BIOSCIENCES, INC.
- Current Assignee: IBIS BIOSCIENCES, INC.
- Current Assignee Address: US CA Carlsbad
- Agency: Casimir Jones, S.C.
- Agent David A. Casimir
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/04
Abstract:
The present invention provides methods for the quantification of an unknown bioagent in a sample by amplification of nucleic acid of the bioagent, and concurrent amplification of a known quantity of a calibration polynucleotide from which are obtained a bioagent identifying amplicon and a calibration amplicon. Upon molecular mass analysis, mass and abundance data are obtained. The identity of the bioagent is then determined from the molecular mass of the bioagent identifying amplicon and the quantity of the identified bioagent in the sample is determined from the abundance data of the bioagent identifying amplicon and the abundance data of the calibration amplicon.
Public/Granted literature
- US20140141502A1 Methods For Concurrent Identification And Quantification Of An Unknown Bioagent Public/Granted day:2014-05-22
Information query
