Invention Grant
- Patent Title: System and method for analyzing DNA mixtures
- Patent Title (中): 分析DNA混合物的系统和方法
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Application No.: US13512959Application Date: 2010-12-02
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Publication No.: US09447474B2Publication Date: 2016-09-20
- Inventor: Ariel Darvasi , Lev Voskoboinik
- Applicant: Ariel Darvasi , Lev Voskoboinik
- Applicant Address: IL Jerusalem
- Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD.
- Current Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD.
- Current Assignee Address: IL Jerusalem
- Agency: Browdy and Neimark, PLLC
- International Application: PCT/IL2010/001019 WO 20101202
- International Announcement: WO2011/067765 WO 20110609
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/02 ; C07H21/04 ; G06F19/18

Abstract:
Provided is a method for determining the presence or absence of an individual's DNA in a sample containing DNA from two or more contributors. A panel of a plurality of single nucleotide polymorphisms (SNPs) is used. For each SNP in the panel, it is determined whether the minor allele of the SNP is present in the sample, and whether the minor allele is present in the individual's DNA. If the number of minor alleles that are present in the individual's DNA that are also present in the DNA sample is above a predetermined threshold, the individual's DNA is concluded to be present in the sample. Also provided is an array of DNA molecules for use in the method, as well as a method for estimating the number of individuals contributing to a DNA containing sample.
Public/Granted literature
- US20120245052A1 SYSTEM AND METHOD FOR ANALYZING DNA MIXTURES Public/Granted day:2012-09-27
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