Invention Grant
US09448296B2 Motion-sensitized driven equilibrium blood-suppression sequence for vessel wall imaging
有权
运动敏化的驱动平衡血液抑制序列用于血管壁成像
- Patent Title: Motion-sensitized driven equilibrium blood-suppression sequence for vessel wall imaging
- Patent Title (中): 运动敏化的驱动平衡血液抑制序列用于血管壁成像
-
Application No.: US12922257Application Date: 2009-02-20
-
Publication No.: US09448296B2Publication Date: 2016-09-20
- Inventor: Jinnan Wang , Vasily Yarnykh , Chun Yuan
- Applicant: Jinnan Wang , Vasily Yarnykh , Chun Yuan
- Applicant Address: US WA Seattle
- Assignee: University of Washington
- Current Assignee: University of Washington
- Current Assignee Address: US WA Seattle
- Agency: Kilpatrick Townsend and Stockton LLP
- International Application: PCT/US2009/034686 WO 20090220
- International Announcement: WO2009/117211 WO 20090924
- Main IPC: A61B5/05
- IPC: A61B5/05 ; G01R33/56 ; G01R33/561 ; G01R33/563

Abstract:
An improved motion-sensitization driven equilibrium (iMSDE) sequence based upon an MLEV-4 sequence is used for black-blood vessel wall imaging. The MSDE pulse pattern that is used us a preparation sequence for other procedures employed to acquire images has been modified to produce the iMSDE sequence by the addition of a second 180 degree refocusing pulse and two motion sensitization gradients. The iMSDE sequence thus includes a group of four radio frequency (RF) pulses, as well as additional magnetic gradient pulses that are not included in the conventional MSDE sequence. Computer simulations indicate that this new pulse sequence is substantially more immune to local B1 inhomogeneity than conventional sequences. In vivo experiments have demonstrated significant signal improvement at high first-order moments (m1) conditions compared to the traditional MSDE sequence.
Public/Granted literature
- US20110092797A1 MOTION-SENSITIZED DRIVEN EQUILIBRIUM BLOOD-SUPPRESSION SEQUENCE FOR VESSEL WALL IMAGING Public/Granted day:2011-04-21
Information query