Invention Grant
US09456984B2 Method for treating fibrosis using siRNA and a retinoid-lipid drug carrier
有权
使用siRNA和类视黄醇 - 脂质药物载体治疗纤维化的方法
- Patent Title: Method for treating fibrosis using siRNA and a retinoid-lipid drug carrier
- Patent Title (中): 使用siRNA和类视黄醇 - 脂质药物载体治疗纤维化的方法
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Application No.: US14294021Application Date: 2014-06-02
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Publication No.: US09456984B2Publication Date: 2016-10-04
- Inventor: Yoshiro Niitsu , Victor Knopov , Joseph E. Payne , Richard P. Witte , Mohammad Ahmadian , Loren A. Perelman , Violetta Akopian , Yasunobu Tanaka , Elena Feinstein , Sharon Avkin-Nahum , Hagar Kalinski , Igor Mett , Kenjiro Minomi , Wenbin Ying , Yun Liu
- Applicant: NITTO DENKO CORPORATION
- Applicant Address: JP Osaka
- Assignee: Nitto Denko Corporation
- Current Assignee: Nitto Denko Corporation
- Current Assignee Address: JP Osaka
- Agency: Baker & Hostetler LLP
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K9/127 ; C12N15/113 ; A61K31/713 ; C07H21/02
Abstract:
What is described is a method for treating a fibrotic disease by administering a pharmaceutical composition comprising a drug carrier, which comprises a lipid and a retinoid, and a double-stranded nucleic acid molecule, which comprises an antisense sequence to mRNA encoding human hsp47.
Public/Granted literature
- US20140356413A1 RETINOID-LIPOSOMES FOR TREATING FIBROSIS Public/Granted day:2014-12-04
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