Invention Grant
US09456992B2 Pharmaceutical composition comprising stable, amorphous, hybrid nanoparticles of at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix forming component
有权
药物组合物，其包含至少一种蛋白激酶抑制剂和至少一种聚合物稳定和基质形成组分的稳定的，无定形的杂化纳米颗粒
- Patent Title: Pharmaceutical composition comprising stable, amorphous, hybrid nanoparticles of at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix forming component
- Patent Title (中): 药物组合物，其包含至少一种蛋白激酶抑制剂和至少一种聚合物稳定和基质形成组分的稳定的，无定形的杂化纳米颗粒
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Application No.: US14371875Application Date: 2013-01-11
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Publication No.: US09456992B2Publication Date: 2016-10-04
- Inventor: Magnus Brisander , Mustafa Demirbüker , Gérald Jesson , Martin Malmsten , Helene Dérand
- Applicant: XSPRAY MICROPARTICLES AB
- Applicant Address: SE Solna
- Assignee: XSPRAY MICROPARTICLES AB
- Current Assignee: XSPRAY MICROPARTICLES AB
- Current Assignee Address: SE Solna
- Agency: Merchant & Gould P.C.
- Priority: SE1250015 20120113; SE1251160 20121012
- International Application: PCT/SE2013/050016 WO 20130111
- International Announcement: WO2013/105895 WO 20130718
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/50 ; A61K38/00 ; A61K9/51 ; A61K31/506 ; A61K31/517 ; A61K31/437 ; A61K31/44 ; A61K31/4439 ; A61K31/4545 ; A61K31/5377 ; A61K47/32 ; A61K47/38
Abstract:
The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.
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