Invention Grant
- Patent Title: Selective inhibitors of undifferentiated cells
- Patent Title (中): 未分化细胞的选择性抑制剂
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Application No.: US14402467Application Date: 2013-05-22
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Publication No.: US09456998B2Publication Date: 2016-10-04
- Inventor: Uri Ben-David , Nissim Benvenisty , Payal Arora , Qing-Fen Gan , Ralph J. Garippa
- Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. , Hoffmann-La Roche Inc.
- Applicant Address: IL Jerusalem US NJ Little Falls
- Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.,Hoffmann-La Roche Inc.
- Current Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.,Hoffmann-La Roche Inc.
- Current Assignee Address: IL Jerusalem US NJ Little Falls
- International Application: PCT/IL2013/050441 WO 20130522
- International Announcement: WO2013/175474 WO 20131128
- Main IPC: A61K31/4409
- IPC: A61K31/4409 ; A61K31/15 ; A61K31/34 ; A61K31/403 ; A61K31/407 ; A61K31/4453 ; A61K31/4545 ; A61K31/4985 ; A61K31/136 ; A61K31/155 ; A61K31/165 ; A61K31/166 ; A61K31/341 ; A61K31/343 ; A61K31/381 ; A61K31/4015 ; A61K31/404 ; A61K31/451 ; A61K31/513 ; G01N33/50
Abstract:
Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
Public/Granted literature
- US20150148359A1 SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS Public/Granted day:2015-05-28
Information query
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