Invention Grant
US09457019B2 Methods for inhibiting tie-2 kinase useful in the treatment of cancer
有权
抑制可用于治疗癌症的2型激酶的方法
- Patent Title: Methods for inhibiting tie-2 kinase useful in the treatment of cancer
- Patent Title (中): 抑制可用于治疗癌症的2型激酶的方法
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Application No.: US14535900Application Date: 2014-11-07
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Publication No.: US09457019B2Publication Date: 2016-10-04
- Inventor: Daniel L. Flynn , Michael D. Kaufman , Bryan D. Smith , Marc Rudoltz
- Applicant: Deciphera Pharmaceuticals, LLC
- Applicant Address: US KS Lawrence
- Assignee: Deciphera Pharmaceuticals, LLC
- Current Assignee: Deciphera Pharmaceuticals, LLC
- Current Assignee Address: US KS Lawrence
- Agency: Cooley LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K31/4709 ; C07D401/14 ; A61K45/06 ; A61K31/337 ; A61K31/351 ; C07K16/40 ; A61K31/357
Abstract:
The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravazation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I.
Public/Granted literature
- US20150246033A1 METHODS FOR INHIBITING TIE-2 KINASE USEFUL IN THE TREATMENT OF CANCER Public/Granted day:2015-09-03
Information query
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