Invention Grant
US09457078B2 Methods for inhibiting C5a with C5a peptides coupled or fused to a carrier protein
有权
用与载体蛋白偶联或融合的C5a肽抑制C5a的方法
- Patent Title: Methods for inhibiting C5a with C5a peptides coupled or fused to a carrier protein
- Patent Title (中): 用与载体蛋白偶联或融合的C5a肽抑制C5a的方法
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Application No.: US13879740Application Date: 2011-12-21
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Publication No.: US09457078B2Publication Date: 2016-10-04
- Inventor: Guenther Staffler , Christine Landlinger , Frank Mattner
- Applicant: Guenther Staffler , Christine Landlinger , Frank Mattner
- Applicant Address: AT Vienna
- Assignee: AFFIRIS AG
- Current Assignee: AFFIRIS AG
- Current Assignee Address: AT Vienna
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP10196232 20101221
- International Application: PCT/EP2011/073599 WO 20111221
- International Announcement: WO2012/085090 WO 20120628
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K39/385 ; A61K39/00 ; C07K14/47
Abstract:
The present invention relates to a vaccine comprising at least one peptide consisting of amino acid sequence LRANISHKDMQLGR (SEQ ID No. 1) or a peptide fragment thereof (SEQ ID No. 2-13) coupled or fused to a carrier protein comprising at least one T cell epitope, wherein said peptide fragment comprises at least 7 amino acid residues and the amino acid sequence KDMQLGR (SEQ ID No: 7) or KDMQLG (SEQ ID No: 23) under the provision that the peptide fragment does not consist of amino acid sequences HKDMQLGR (SEQ ID No: 16) and HKDMQLG (SEQ ID No: 22).
Public/Granted literature
- US20130216565A1 VACCINES BASED ON PEPTIDES OF THE COMPLEMENT PROTEIN C5A Public/Granted day:2013-08-22
Information query
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