Invention Grant
US09457079B2 Methods for producing enteroendocrine cells that make and secrete insulin
有权
产生和分泌胰岛素的肠内分泌细胞的方法
- Patent Title: Methods for producing enteroendocrine cells that make and secrete insulin
- Patent Title (中): 产生和分泌胰岛素的肠内分泌细胞的方法
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Application No.: US13697792Application Date: 2011-05-12
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Publication No.: US09457079B2Publication Date: 2016-10-04
- Inventor: Chutima Talchai , Domenico Accili
- Applicant: Chutima Talchai , Domenico Accili
- Applicant Address: US NY New York
- Assignee: The Trustees Of Columbia University In The City Of New York
- Current Assignee: The Trustees Of Columbia University In The City Of New York
- Current Assignee Address: US NY New York
- Agency: Beusse Wolter Sanks & Maire PLLC
- Agent Judith A. Evans; Timothy H. Van Dyke
- International Application: PCT/US2011/036360 WO 20110512
- International Announcement: WO2011/143511 WO 20111117
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/7088 ; C12N15/113 ; G01N33/50

Abstract:
Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more Foxo proteins or biologically active fragments or variants thereof.
Public/Granted literature
- US20130216554A1 Methods for Producing Enteroendocrine Cells That Make and Secrete Insulin Public/Granted day:2013-08-22
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