Invention Grant
US09457097B2 Mucosal delivery of therapeutic molecules, proteins, or particles coupled to ceramide lipids
有权
粘膜递送治疗分子，蛋白质或与神经酰胺脂质偶联的颗粒
- Patent Title: Mucosal delivery of therapeutic molecules, proteins, or particles coupled to ceramide lipids
- Patent Title (中): 粘膜递送治疗分子，蛋白质或与神经酰胺脂质偶联的颗粒
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Application No.: US13062638Application Date: 2009-09-04
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Publication No.: US09457097B2Publication Date: 2016-10-04
- Inventor: Wayne I. Lencer , Daniel J F Chinnapen , Randy Mrsny
- Applicant: Wayne I. Lencer , Daniel J F Chinnapen , Randy Mrsny
- Applicant Address: US MA Boston
- Assignee: Children's Medical Corporation
- Current Assignee: Children's Medical Corporation
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2009/004986 WO 20090904
- International Announcement: WO2010/027479 WO 20100311
- Main IPC: C07K17/10
- IPC: C07K17/10 ; C12N5/071 ; A61K38/26 ; A61K47/48
Abstract:
Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER).
Public/Granted literature
- US20120252727A1 MUCOSAL DELIVERY OF THERAPEUTIC MOLECULES, PROTEINS, OR PARTICLES COUPLED TO CERAMIDE LIPIDS Public/Granted day:2012-10-04
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