- Patent Title: Heteroaryl compounds useful as inhibitors of E1 activating enzymes
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Application No.: US14827556Application Date: 2015-08-17
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Publication No.: US09458108B2Publication Date: 2016-10-04
- Inventor: Christopher F. Claiborne , Stephen Critchley , Steven P. Langston , Hirotake Mizutani , Edward J. Olhava , Stephane Peluso , Stepan Vyskocil , Gabriel S. Weatherhead
- Applicant: MILLENNIUM PHARMACEUTICALS, INC.
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Main IPC: C07D213/56
- IPC: C07D213/56 ; A61K31/443 ; C07D213/82 ; C07D213/69 ; C07D239/42 ; C07D401/04 ; C07D403/04 ; C07D471/04 ; C07D471/08 ; C07D473/34 ; C07D473/30 ; A61K31/53 ; C07D251/18 ; C07D251/48 ; C07D213/74 ; C07D401/06 ; C07D487/04
Abstract:
This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.
Public/Granted literature
- US20160039761A1 HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF E1 ACTIVATING ENZYMES Public/Granted day:2016-02-11
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