Invention Grant
US09458123B2 Methods, pharmaceutical compositions, therapeutic systems, and compounds for treating B cell malignancies
有权
方法，药物组合物，治疗系统和用于治疗B细胞恶性肿瘤的化合物
- Patent Title: Methods, pharmaceutical compositions, therapeutic systems, and compounds for treating B cell malignancies
- Patent Title (中): 方法，药物组合物，治疗系统和用于治疗B细胞恶性肿瘤的化合物
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Application No.: US14378082Application Date: 2013-02-15
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Publication No.: US09458123B2Publication Date: 2016-10-04
- Inventor: Jiyong Zhao
- Applicant: Jiyong Zhao
- Applicant Address: US NY Rochester
- Assignee: University of Rochester
- Current Assignee: University of Rochester
- Current Assignee Address: US NY Rochester
- Agency: LeClairRyan, a Professional Corporation
- International Application: PCT/US2013/026330 WO 20130215
- International Announcement: WO2013/123320 WO 20130822
- Main IPC: C07D307/71
- IPC: C07D307/71 ; A61K45/06 ; A61K31/345
Abstract:
This invention relates to a method of treating B cell malignancies, which involves administering to a subject a compound having a structure of formula (I) to cause cell death of a B cell malignancy, thereby treating the B cell malignancy in the subject. Also disclosed are a method of causing cell death of malignant B cells, pharmaceutical compositions and therapeutic systems comprising a compound having a structure of formula (I), and a compound having a structure of formula (I).
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