Invention Grant
- Patent Title: Catechol O-methyltransferase activity inhibiting compounds
- Patent Title (中): 儿茶酚O-甲基转移酶活性抑制化合物
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Application No.: US14403023Application Date: 2013-05-23
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Publication No.: US09458128B2Publication Date: 2016-10-04
- Inventor: Marko Ahlmark , David Din Belle , Mika Kauppala , Anne Luiro , Taina Pajunen , Jarmo Pystynen , Eija Tiainen , Matti Vaismaa , Josef Messinger
- Applicant: Orion Corporation
- Applicant Address: FI Espoo
- Assignee: ORION CORPORATION
- Current Assignee: ORION CORPORATION
- Current Assignee Address: FI Espoo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- International Application: PCT/FI2013/000026 WO 20130523
- International Announcement: WO2013/175053 WO 20131128
- Main IPC: C07C205/56
- IPC: C07C205/56 ; C07C255/57 ; C07C255/53 ; C07C255/51 ; C07C229/42 ; C07D333/60 ; C07C255/54 ; C07D333/24 ; C07C311/29 ; C07D207/337 ; C07D277/30 ; C07D295/192 ; C07D213/57 ; C07D307/54 ; C07D307/80 ; C07D309/06 ; C07D309/12 ; C07D231/12 ; C07D231/14 ; C07D333/28 ; C07D333/70 ; C07D277/34 ; C07D277/74 ; C07D211/14 ; C07D295/155 ; C07D213/62 ; C07C255/59 ; C07C309/66 ; C07C317/46 ; C07C323/62 ; A61K31/198 ; A61K31/277 ; A61K31/341 ; A61K31/343 ; A61K31/381 ; A61K31/382 ; A61K31/40 ; A61K31/5377 ; C07C323/29 ; C07D307/81 ; C07D309/22
Abstract:
Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
Public/Granted literature
- US20150218124A1 CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS Public/Granted day:2015-08-06
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