Invention Grant
US09458132B2 Therapeutic compounds and compositions and their use as PKM2 modulators
有权
治疗化合物和组合物及其作为PKM2调节剂的用途
- Patent Title: Therapeutic compounds and compositions and their use as PKM2 modulators
- Patent Title (中): 治疗化合物和组合物及其作为PKM2调节剂的用途
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Application No.: US14441746Application Date: 2013-11-08
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Publication No.: US09458132B2Publication Date: 2016-10-04
- Inventor: Giovanni Cianchetta , Janeta Popovici-Muller , Jeffrey O. Saunders , Robert Zahler
- Applicant: AGIOS PHARMACEUTICALS, INC.
- Applicant Address: US MA Cambridge
- Assignee: AGIOS PHARMACEUTICALS, INC
- Current Assignee: AGIOS PHARMACEUTICALS, INC
- Current Assignee Address: US MA Cambridge
- International Application: PCT/US2013/069193 WO 20131108
- International Announcement: WO2014/074848 WO 20140515
- Main IPC: C07D205/02
- IPC: C07D205/02 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D205/04
Abstract:
Compositions comprising compounds of general formula (I) that modulate pyruvate kinase are described herein. Also described herein are methods of using the compounds that modulate pyruvate kinase in the treatment of diseases.
Public/Granted literature
- US20150307473A1 THERAPEUTIC COMPOUNDS AND COMPOSITIONS AND THEIR USE AS PKM2 MODULATORS Public/Granted day:2015-10-29
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