Invention Grant
- Patent Title: Sulfonamide compounds and uses as TNAP inhibitors
- Patent Title (中): 磺酰胺化合物和用作TNAP抑制剂
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Application No.: US14379475Application Date: 2013-02-21
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Publication No.: US09458147B2Publication Date: 2016-10-04
- Inventor: Anthony B. Pinkerton , Russell Dahl , Nicholas D. P. Cosford , Jose Luis Millan
- Applicant: Sanford-Burnham Medical Research Institute
- Applicant Address: US CA La Jolla
- Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- Current Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- Current Assignee Address: US CA La Jolla
- Agency: Wilson, Sonsini, Goodrich & Rosati
- International Application: PCT/US2013/027191 WO 20130221
- International Announcement: WO2013/126608 WO 20130829
- Main IPC: C07D213/76
- IPC: C07D213/76 ; C07D215/38 ; C07D409/04 ; C07D405/04 ; C07D409/12 ; C07D417/04 ; C07D405/12 ; C07D401/12 ; C07D401/04 ; A61K31/44 ; A61K31/50 ; C07D213/80 ; C07D213/82 ; C07D231/42 ; C07D333/36 ; C07D237/20 ; C07D239/69 ; C07D241/22 ; C07D261/16 ; C07D263/50 ; C07D271/113 ; C07D277/52 ; C07D285/135
Abstract:
Described herein are compounds that modulate the activity of TNAP. In some embodiments, the compounds described herein inhibit TNAP. In certain embodiments, the compounds described herein are useful in the treatment of conditions associated with hyper-mineralization.
Public/Granted literature
- US20150011551A1 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS Public/Granted day:2015-01-08
Information query
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