Invention Grant
US09458176B2 Tetrahydroimidazo(1,5-D)[1,4]oxazepine derivative 有权
四氢咪唑并(1,5-D)[1,4]氧氮杂衍生物

Tetrahydroimidazo(1,5-D)[1,4]oxazepine derivative
Abstract:
A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof works as an mGluR2 antagonist, and is applicable as a therapeutic agent for neurological disorders related to glutamate dysfunction and diseases involving the mGluR2, such as Alzheimer's disease: wherein R is a hydrogen atom, a C1-6 alkyl group or the like, R1 is a C1-6 alkyl group, a C1-6 alkoxy group or the like, R2 is a halogen atom, a C1-6 alkyl group, a C1-6 alkoxy group or the like, R3 is a hydrogen atom, a C1-6 alkyl group or the like, and R4 is a C1-6 alkyl group or the like.
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