Invention Grant
US09458224B2 Method for obtaning thin fibril collagen by contacting native collagen with an antibody
有权
通过将天然胶原蛋白与抗体接触来获得薄原纤维胶原蛋白的方法
- Patent Title: Method for obtaning thin fibril collagen by contacting native collagen with an antibody
- Patent Title (中): 通过将天然胶原蛋白与抗体接触来获得薄原纤维胶原蛋白的方法
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Application No.: US12419689Application Date: 2009-04-07
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Publication No.: US09458224B2Publication Date: 2016-10-04
- Inventor: Joseph Orgel , Olga Antipova
- Applicant: Joseph Orgel , Olga Antipova
- Applicant Address: US IL Northbrook
- Assignee: Matrix Odyssey, LLC
- Current Assignee: Matrix Odyssey, LLC
- Current Assignee Address: US IL Northbrook
- Agency: K&L Gates LLP
- Main IPC: A01N1/02
- IPC: A01N1/02 ; C07K14/78
Abstract:
A collagen material having a form of thin fibrils generally free of fibril-bundling proteogylcan interactions, and a method for providing the thin fibril collagen material from native collagen fibers. The method uses proteoglycan antibodies to disassociate the proteoglycan interactions in bundled collagen fibrils to provide the constituent fibrils. The process can be used as a model for arthritis and the resulting fibrils can be used to form new extracellular matrix biomaterials and new tissues.
Public/Granted literature
- US20100255457A1 THIN FIBRIL COLLAGEN MATERIAL AND METHOD FOR MAKING THIN FIBRIL COLLAGEN FROM NATIVE COLLAGEN FIBERS Public/Granted day:2010-10-07
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