Invention Grant
US09458238B2 Nucleic acid molecules encoding antibodies which bind CCR4 and uses thereof
有权
编码结合CCR4的抗体的核酸分子及其用途
- Patent Title: Nucleic acid molecules encoding antibodies which bind CCR4 and uses thereof
- Patent Title (中): 编码结合CCR4的抗体的核酸分子及其用途
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Application No.: US14515892Application Date: 2014-10-16
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Publication No.: US09458238B2Publication Date: 2016-10-04
- Inventor: Urs Beat Hagemann , Remko Albert Griep , Herald Reiersen , Sergej Michailovi{hacek over (c)} Kiprijanov
- Applicant: Affitech Research AS
- Applicant Address: GB London
- Assignee: Cancer Research Technology Limited
- Current Assignee: Cancer Research Technology Limited
- Current Assignee Address: GB London
- Agency: Rothwell, Figg, Ernst & Manbeck, p.c.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N5/10 ; C12N7/01 ; C12N15/63 ; C07K16/28 ; A61K39/00
Abstract:
The present invention provides antibodies which bind to an epitope in the extracellular domain of human CC chemokine receptor 4 (CCR4) and which are capable of inhibiting the binding of macrophage-derived chemokine (MDC) and/or thymus and activation regulated chemokine (TARC) to CCR4. Also provided are inter alia immunoconjugates and compositions comprising such antibodies and methods and uses involving such antibodies, particularly in the medical and diagnostic fields.
Public/Granted literature
- US20150104831A1 Antibodies and Uses Thereof Public/Granted day:2015-04-16
Information query
IPC分类:
