Invention Grant
- Patent Title: Single chain multivalent binding protein compositions and methods
- Patent Title (中): 单链多价结合蛋白组合物和方法
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Application No.: US14141500Application Date: 2013-12-27
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Publication No.: US09458244B2Publication Date: 2016-10-04
- Inventor: Lorenzo Benatuil , Chung-Ming Hsieh
- Applicant: AbbVie, Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Lathrop & Gage LLP
- Agent James H. Velema, Esq.
- Main IPC: C40B40/10
- IPC: C40B40/10 ; C07K16/46 ; C07K16/22 ; C07K16/24
Abstract:
Provided are protein, nucleic acid, and cellular libraries of single chain multivalent binding proteins (e.g., scDVD and scDVDFab molecules) and methods of using these of these libraries for the screening of single chain multivalent binding proteins using cell surface display technology (e.g., yeast display).
Public/Granted literature
- US20140221621A1 SINGLE-CHAIN MULTIVALENT BINDING PROTEIN COMPOSITIONS AND METHODS Public/Granted day:2014-08-07
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