A method for pre-emptively reducing the production of water in an oil and gas well is provided. In one embodiment, a drill-in fluid having a relative permeability modifier (RPM) capable of impeding the production of water is introduced into the wellbore during drilling operations. In a second embodiment, a completion fluid having a relative permeability modifier (RPM) capable of impeding the production of water is introduced into the wellbore during completion operations. The drill-in fluid or completion fluid may further include an organosilicon compound to increase flow resistance and extend the effective RPM permeability application range.