Invention Grant
US09458427B2 IFNγR2 compositions and methods of inhibiting neuronal cell death
有权
IFNγR2组合物和抑制神经元细胞死亡的方法
- Patent Title: IFNγR2 compositions and methods of inhibiting neuronal cell death
- Patent Title (中): IFNγR2组合物和抑制神经元细胞死亡的方法
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Application No.: US14279432Application Date: 2014-05-16
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Publication No.: US09458427B2Publication Date: 2016-10-04
- Inventor: Shigemi Matsuyama
- Applicant: Case Western Reserve University
- Applicant Address: US OH Cleveland
- Assignee: Case Western Reserve University
- Current Assignee: Case Western Reserve University
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: A61K38/04
- IPC: A61K38/04 ; C07K14/715 ; C12N5/0793 ; A61K38/08 ; A61K38/07 ; C07K16/28
Abstract:
A method of inhibiting β-amyloid (Aβ) induced neuronal cell death includes administering to a neuronal cell exposed to a neurotoxic amount of Aβ a therapeutically effective amount of cell penetrating peptide (CPP). The CPP has an amino acid sequence that has at least 80% sequence identity to about 5 to about 41 consecutive amino acids of SEQ ID NO: 1.
Public/Granted literature
- US20140256039A1 COMPOSITIONS AND METHODS OF INHIBITING NEURONAL CELL DEATH Public/Granted day:2014-09-11
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