Invention Grant
- Patent Title: Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
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Application No.: US14459876Application Date: 2014-08-14
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Publication No.: US09458442B2Publication Date: 2016-10-04
- Inventor: Ping Jiang , H. Michael Shepard , Lei Huang
- Applicant: Ping Jiang , H. Michael Shepard , Lei Huang
- Applicant Address: US CA San Diego
- Assignee: Halozyme, Inc.
- Current Assignee: Halozyme, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Dentons US LLP
- Agent Stephanie Seidman
- Main IPC: C07K14/81
- IPC: C07K14/81 ; C12N9/26 ; A61K38/47 ; G01N33/574 ; G01N33/566 ; G01N33/68 ; A61K47/10 ; C07K14/47
Abstract:
Methods and diagnostic agents for identification of subjects for cancer treatment with an anti-hyaluronan agent, such as a hyaluronan-degrading enzyme, are provided. Diagnostic agents for the detection and quantification of hyaluronan in a biological sample and monitoring cancer treatment with an anti-hyaluronan agent, for example a hyaluronan-degrading enzyme, are provided. Combinations and kits for use in practicing the methods also are provided.
Public/Granted literature
- US20150218544A9 COMPANION DIAGNOSTIC FOR ANTI-HYALURONAN AGENT THERAPY AND METHODS OF USE THEREOF Public/Granted day:2015-08-06
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