Invention Grant
US09458457B2 Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA
有权
通过双链RNA特异性抑制α-1抗胰蛋白酶的方法和组合物
- Patent Title: Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA
- Patent Title (中): 通过双链RNA特异性抑制α-1抗胰蛋白酶的方法和组合物
-
Application No.: US14323299Application Date: 2014-07-03
-
Publication No.: US09458457B2Publication Date: 2016-10-04
- Inventor: Bob D. Brown , Henryk T. Dudek
- Applicant: Dicerna Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Christopher R. Cowles
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113
Abstract:
This invention relates to compounds, compositions, and methods useful for reducing α-1 antitrypsin target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.
Public/Granted literature
- US20150011607A1 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF ALPHA-1 ANTITRYPSIN BY DOUBLE-STRANDED RNA Public/Granted day:2015-01-08
Information query
IPC分类:
