Invention Grant
US09458459B2 Methods for enhancing utrophin production via inhibition of microRNA
有权
通过抑制microRNA增强utrophin产生的方法
- Patent Title: Methods for enhancing utrophin production via inhibition of microRNA
- Patent Title (中): 通过抑制microRNA增强utrophin产生的方法
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Application No.: US14547795Application Date: 2014-11-19
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Publication No.: US09458459B2Publication Date: 2016-10-04
- Inventor: Catherine Moorwood , Utpal Basu , Gopal Patel , Olga Lozynska , Tejvir S. Khurana
- Applicant: The Trustees of the University of Pennsylvania
- Applicant Address: US PA Philadelphia
- Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Current Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Current Assignee Address: US PA Philadelphia
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Agent Mark S. Cohen
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61P21/00 ; C12N15/113 ; C07K14/47
Abstract:
This invention provides a method for enhancing utrophin protein production in a cell by inhibiting an utrophin microRNA molecule. Moreover, the invention provides that methods for enhancing utrophin protein production in a muscle cell are used for treating a muscular dystrophy and/or other myopathies.
Public/Granted literature
- US20160046931A1 METHODS FOR ENHANCING UTROPHIN PRODUCTION VIA INHIBITION OF MICRORNA Public/Granted day:2016-02-18
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