Invention Grant
US09458463B2 Method for treatment of diabetes by a small molecule inhibitor for GRK5
有权
用于GRK5的小分子抑制剂治疗糖尿病的方法
- Patent Title: Method for treatment of diabetes by a small molecule inhibitor for GRK5
- Patent Title (中): 用于GRK5的小分子抑制剂治疗糖尿病的方法
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Application No.: US14554714Application Date: 2014-11-26
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Publication No.: US09458463B2Publication Date: 2016-10-04
- Inventor: Mathias Falcenberg , Axel Ullrich
- Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
- Applicant Address: DE Munich
- Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
- Current Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
- Current Assignee Address: DE Munich
- Agency: Amin, Turocy & Watson, LLP
- Priority: EP10075383 20100903
- Main IPC: A61K31/00
- IPC: A61K31/00 ; C12N15/113
Abstract:
The present invention is related to compound capable of modulating the activity and/or expression of the protein kinase GRK5, thereby enhancing the expression and/or release of insulin. The invention is further related to methods of identifying said compounds for the treatment of diseases of the carbohydrate metabolism. The invention is further related to methods of treatment of diseases of the carbohydrate metabolism, particularly diabetes mellitus type 2.
Public/Granted literature
- US20150079108A1 KINASES AS TARGETS FOR ANTI-DIABETIC THERAPY Public/Granted day:2015-03-19
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