Techniques of Transmission Control Protocol (TCP) packet transmission for wireless communication are provided for a user equipment (UE). The UE receives a plurality of TCP packets on a downlink channel from a network. In response, the UE generates a plurality of TCP Acknowledgment (ACK) packets corresponding to the plurality of received TCP packets. The plurality of TCP ACK packets is prioritized based on certain criteria. A TCK ACK packet with a highest priority among the plurality of TCP ACK packets is selected. The selected highest priority TCP ACK packet is then sent to the network on an uplink channel.