The present disclosure is directed to a system and method for performing out-of-order message filtering with aging. The system and method can be used in a destination device that can receive messages out-of-order (i.e., in a different order than they were transmitted) from a source device. The system and method can filter-out or flag for appropriate handling these messages received out-of-order. To perform the above noted message filtering functionality, the system and method uses a database constructed from a content-addressable memory (CAM) and a random-access memory (RAM) to respectively remember source identifiers and sequence identifiers associated with previously received messages. A source identifier identifies the source of a message, and a sequence identifier identifies the transmission order of the message among the messages transmitted from the particular source. Each message can include a source identifier and a corresponding sequence identifier.