Invention Grant
US09480676B2 Use of PDE4 inhibitors and combinations thereof for the treatment of cystic fibrosis
有权
使用PDE4抑制剂及其组合用于治疗囊性纤维化
- Patent Title: Use of PDE4 inhibitors and combinations thereof for the treatment of cystic fibrosis
- Patent Title (中): 使用PDE4抑制剂及其组合用于治疗囊性纤维化
-
Application No.: US14712595Application Date: 2015-05-14
-
Publication No.: US09480676B2Publication Date: 2016-11-01
- Inventor: Peter H. Schafer , Shimon Korish
- Applicant: Celgene Corporation
- Applicant Address: US NJ Summit
- Assignee: Celgene Corporation
- Current Assignee: Celgene Corporation
- Current Assignee Address: US NJ Summit
- Agency: Jones Day
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61K31/4035 ; A61K45/06 ; A61K31/443
Abstract:
Methods of treating cystic fibrosis by administering a PDE4 inhibitor in combination with one or more cystic fibrosis transmembrane conductance regulator (CFTR) potentiators, including ivacaftor, and/or one or more CFTR correctors, including lumacaftor. Pharmaceutical compositions, dosage forms, and kits suitable for use in methods of the invention are also disclosed.
Public/Granted literature
- US20150328187A1 USE OF PDE4 INHIBITORS AND COMBINATIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS Public/Granted day:2015-11-19
Information query
