Invention Grant
US09480734B2 Immunogenic composition of killed leptospira bacteria 有权
灭活的钩端螺旋体细菌的免疫原性组成

  • Patent Title: Immunogenic composition of killed leptospira bacteria
  • Patent Title (中): 灭活的钩端螺旋体细菌的免疫原性组成
  • Application No.: US14420946
    Application Date: 2013-08-16
  • Publication No.: US09480734B2
    Publication Date: 2016-11-01
  • Inventor: Henricus Leo Bernardus Maria KlaasenEric Onno Rijke
  • Applicant: Intervet Inc.
  • Applicant Address: US NJ Madison
  • Assignee: Intervet Inc.
  • Current Assignee: Intervet Inc.
  • Current Assignee Address: US NJ Madison
  • Priority: EP12180793 20120817
  • International Application: PCT/EP2013/067133 WO 20130816
  • International Announcement: WO2014/027084 WO 20140220
  • Main IPC: A61K39/02
  • IPC: A61K39/02 A61K47/18 A61K39/00
Immunogenic composition of killed leptospira bacteria
Abstract:
The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in an ethylenediaminetetraacetic acid solution. The invention also pertains to a vaccine to protect an animal against an infection with leptospira bacteria, wherein the vaccine comprises this composition. Also, the invention pertains to the use of ethylenediaminetetraacetic acid to stabilize an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the ethylenediaminetetraacetic acid in the carrier.
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