A power control module including first port for receiving supply voltage from host power supply, second port for providing output voltage to power one or more data storage device components, isolation circuit coupled to first and second ports, driver including output coupled to control terminal of isolation circuit, voltage booster including input for receiving supply voltage and output for providing boost voltage to supply terminal of driver, voltage limiter operable to limit boost voltage to a limited boost voltage, and control circuitry coupled to drive input and operable to cause the isolation circuit to be in closed state during normal operating mode by causing the driver to apply limited boost voltage to the control terminal of the isolation circuit, thereby enabling the isolation circuit to provide over-voltage protection to one or more data storage device components by limiting output voltage at second port to less than the limited boost voltage.