A method and system are proposed to obtain quantitative data about the shape of a biological structure, and especially a heart ventricle. A set of three-dimensional input meshes are generated from MRI data. They represent the shape of a ventricle at successive times. The input meshes are used to generate a set of three-dimensional morphed meshes which have the same number of vertices as each other, and have respective shapes which are the shapes of corresponding ones of the input meshes. Then, for each of the times, shape analysis is performed to obtain a curvedness value at each of a plurality of corresponding locations in the morphed meshes. The curvedness value may be used to obtain a curvedness rate at each of the locations, indicative of the rate of change of curvedness with time at each of the locations.