A message from a source computer that includes message information indicating a destination target computer system to receive the message, is received. The received message in a storage component, is stored. An entry to a virtual queue for the received message, wherein the entry in the virtual queue points to a memory address of the received message that is stored in the message component, is created. Responsive to determining that the destination target computer system is available, the received message to a physical queue component and assigning an expiration condition to the received message is enqueued. The enqueued message to the destination target computer system is transmitted. Responsive to determining that the expiration condition for the received message is met, the received message from the physical queue is removed.