Provided are embodiments of systems and methods related to labeling, and more particular to labeling that may be guided by regulatory requirements. A system comprises an electronic device having a user interface capable of displaying a WYSIWYG image of a label and providing access to regulatory information related to the displayed label. The system may further determine compliance with regulatory guidelines by a user-edited label. The electronic device may be, or be in communication with, a label printer to initiate printing of a displayed label. A method includes the steps of accessing a WYSIWYG image of a label and accessing regulatory information related to such label using a handheld electronic device. The method may further include the steps of verifying compliance of a label with regulatory guidelines or requirements and initiating printing of such label, which may be adhesive.