Embodiments of the present invention provide an interference coordination method, a base station, and a communication system. The method includes: acquiring first user channel state information on a first time-frequency resource on which interference coordination is to be performed; acquiring second user channel state information on the first time-frequency resource; pairing a first user and a second user according to the first user channel state information and the second user channel state information to obtain transmit power and a precoding matrix that are corresponding to the second user; and transmitting data to the second user on the first time-frequency resource according to the transmit power and the precoding matrix, but not transmitting data to the first user on the first time-frequency resource.