Invention Grant
US09533002B2 Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-β
有权
通过调节热休克蛋白（HSP）90-β治疗代谢综合征的方法
- Patent Title: Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-β
- Patent Title (中): 通过调节热休克蛋白（HSP）90-β治疗代谢综合征的方法
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Application No.: US13902354Application Date: 2013-05-24
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Publication No.: US09533002B2Publication Date: 2017-01-03
- Inventor: Niven Rajin Narain , Rangaprasad Sarangarajan , Vivek K. Vishnudas , Enxuan Jing
- Applicant: Niven Rajin Narain , Rangaprasad Sarangarajan , Vivek K. Vishnudas , Enxuan Jing
- Applicant Address: US TN Nashville
- Assignee: Berg LLC
- Current Assignee: Berg LLC
- Current Assignee Address: US TN Nashville
- Agency: McCarter & English, LLP
- Agent Elizabeth A. Hanley, Esq.; Jill Mello
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/11 ; A61K31/7056 ; A61K31/192 ; A61K31/352 ; A61K31/416 ; A61K31/713 ; C07K16/18 ; C12Q1/68 ; G01N33/53 ; C07K14/47 ; C12N15/113 ; G01N33/68 ; A61K31/19 ; A61K31/366
Abstract:
The invention provides methods of treatment of metabolic syndrome with HSP90 inhibitors, particularly HSP90β inhibitors. The invention provides methods of diagnosis and monitoring of metabolic syndrome using HSP90, particularly HSP90β, expression and activity level.
Public/Granted literature
- US20140154266A1 METHODS OF TREATING A METABOLIC SYNDROME BY MODULATING HEAT SHOCK PROTEIN (HSP) 90-BETA Public/Granted day:2014-06-05
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