Invention Grant
- Patent Title: Vaccine for intrauterine disease
- Patent Title (中): 疫苗用于子宫内疾病
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Application No.: US14647623Application Date: 2013-10-08
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Publication No.: US09533034B2Publication Date: 2017-01-03
- Inventor: Rodrigo Carvalho Bicalho , Robert Owen Gilbert , Vinicius Machado , Marcela Bicalho
- Applicant: Cornell University
- Applicant Address: US NY Ithaca
- Assignee: Cornell University
- Current Assignee: Cornell University
- Current Assignee Address: US NY Ithaca
- Agency: Hodgson Russ LLP
- International Application: PCT/US2013/063866 WO 20131008
- International Announcement: WO2014/084964 WO 20140605
- Main IPC: A61K39/05
- IPC: A61K39/05 ; A61K39/114 ; A61J1/18 ; C12N1/20 ; A61K39/108 ; C07K14/195 ; C07K14/245 ; A61K39/00
Abstract:
Provided are compositions and methods for use in prophylaxis of puerperal metritis and improving reproductive function of ruminants. The methods and compositions are for subcutaneous administration and are provided as veterinary compositions and as articles of manufacture. The veterinary composition can contain whole cells selected from whole cells of Escherichia coli (E. coli), Trueperella pyogenes (T. pyogenes), Fusobacterium necrophorum (F. necrophorum) and combinations thereof; and/or proteins selected from F. necrophorum leukotoxin (LKT), E. coli type 1 fimbrial adhesin (FimH), T. pyogenes pyolysin (PLO), and all combinations of the whole cells and the proteins.
Public/Granted literature
- US20150335725A1 VACCINE FOR INTRAUTERINE DISEASE Public/Granted day:2015-11-26
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