Invention Grant
- Patent Title: Controlled release formulations of levodopa and uses thereof
- Patent Title (中): 左旋多巴的控制释放制剂及其用途
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Application No.: US14958975Application Date: 2015-12-04
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Publication No.: US09533046B2Publication Date: 2017-01-03
- Inventor: Ann Hsu , Jim Kou , Laman Alani
- Applicant: Impax Laboratories, Inc.
- Applicant Address: US CA Hayward
- Assignee: Impax Laboratories, Inc.
- Current Assignee: Impax Laboratories, Inc.
- Current Assignee Address: US CA Hayward
- Agency: Florek & Endres PLLC
- Main IPC: A61K31/185
- IPC: A61K31/185 ; A61K9/24 ; A61K9/26 ; A61K47/12 ; A61K9/16 ; A61K9/20 ; A61K9/28 ; A61K9/50 ; A61K31/137 ; A61K31/198 ; A61K45/06 ; C07C229/36 ; A61K9/00 ; A61K31/197 ; A61K47/34 ; A61K47/38

Abstract:
The current invention provides a controlled release oral solid formulation of levodopa comprising levodopa, a decarboxylase inhibitor, and a carboxylic acid. Also provided by this invention is multiparticulate, controlled release oral solid formulations of levodopa comprising: i) a controlled release component comprising a mixture of levodopa, a decarboxylase inhibitor and a rate controlling excipient; ii) a carboxylic acid component; and iii) an immediate release component comprising a mixture of levodopa and a decarboxylase inhibitor.
Public/Granted literature
- US20160089438A1 CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND USES THEREOF Public/Granted day:2016-03-31
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