The present invention relates to a structural component 1; 21; 31; 41, in particular for a motor vehicle body, comprising a cold-formed first formed part 2; 32; 42 and a warm-formed and hardened second formed part 3; 23; 33 with a variable thickness along a longitudinal extension L2 of the second formed part 3; 23; 33, wherein the second formed part 3; 23; 33 has a connection portion 7; 27; 37 for being connected to the first formed part 2; 32; 42, wherein the connection portion 7; 27; 37 is distanced from an outer edge 13 of the first formed part 2; 32; 42 such, that the structural component 1; 21; 31; 41 has a one-layered flange portion 12 of the first formed part 2; 32; 42 between the connection portion 7; 27; 37 and the outer edge 13, and wherein the first formed part 2; 32; 42 and the second formed part 3; 23; 33 are connected to each other by means of a high energy beam welding seam 19 along a connection edge 18 of the connection portion 7; 17; 27. Furthermore, the present invention relates to a method for manufacturing a structural component 1; 21; 31; 41.