Invention Grant
US09533959B2 Methods of regioselective synthesis of 2,4-disubstituted pyrimidines
有权
区域选择性合成2,4-二取代嘧啶的方法
- Patent Title: Methods of regioselective synthesis of 2,4-disubstituted pyrimidines
- Patent Title (中): 区域选择性合成2,4-二取代嘧啶的方法
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Application No.: US15043717Application Date: 2016-02-15
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Publication No.: US09533959B2Publication Date: 2017-01-03
- Inventor: Jean-Damien Charrier , Michael Edward O'Donnell
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Andrew N. Weber; Jonathan P. O'Brien
- Main IPC: C07D239/34
- IPC: C07D239/34 ; C07D239/47 ; C07D403/14 ; C07D239/48 ; C07D401/14
Abstract:
The present invention relates to the novel regioselective syntheses of 2,4-disubstituted pyrimidines through sequential nucleophilic aromatic substitutions.
Public/Granted literature
- US20160159749A1 METHODS OF REGIOSELECTIVE SYNTHESIS OF 2,4-DISUBSTITUTED PYRIMIDINES Public/Granted day:2016-06-09
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