Invention Grant
- Patent Title: Preparation process of carboxylic acid derivatives and intermediates thereof
- Patent Title (中): 羧酸衍生物的制备方法及其中间体
-
Application No.: US14410517Application Date: 2013-06-28
-
Publication No.: US09533960B2Publication Date: 2017-01-03
- Inventor: Nicolas Tesson , Montserrat Trilla Castaño
- Applicant: KERN PHARMA, S.L.
- Applicant Address: ES Terrassa
- Assignee: KERN PHARMA, S.L.
- Current Assignee: KERN PHARMA, S.L.
- Current Assignee Address: ES Terrassa
- Agency: Squire Patton Boggs (US) LLP
- Priority: EP12382259 20120629
- International Application: PCT/EP2013/063649 WO 20130628
- International Announcement: WO2014/001511 WO 20140103
- Main IPC: C07C51/43
- IPC: C07C51/43 ; C07C229/04 ; C07C63/331 ; C07C59/64 ; C07D239/62 ; C07D239/34 ; C07C51/41

Abstract:
A cocrystal of (S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid and an amino acid, in particular L-valine or L-2-aminobutyric acid, their preparation processes, as well as the preparation process of Ambrisentan or Darusentan using any of the cocrystals of the invention.
Public/Granted literature
- US20150299140A1 PREPARATION PROCESS OF CARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES THEREOF Public/Granted day:2015-10-22
Information query