Invention Grant
US09533970B2 Multisubstituted aromatic compounds as serine protease inhibitors
有权
多取代芳族化合物作为丝氨酸蛋白酶抑制剂
- Patent Title: Multisubstituted aromatic compounds as serine protease inhibitors
- Patent Title (中): 多取代芳族化合物作为丝氨酸蛋白酶抑制剂
-
Application No.: US14776612Application Date: 2014-03-17
-
Publication No.: US09533970B2Publication Date: 2017-01-03
- Inventor: Kevin Michael Short , Son Minh Pham , David Charles Williams , David Ben Kita
- Applicant: VERSEON CORPORATION
- Applicant Address: US CA Fremont
- Assignee: VERSEON CORPORATION
- Current Assignee: VERSEON CORPORATION
- Current Assignee Address: US CA Fremont
- Agency: Davis Wright Tremaine LLP
- International Application: PCT/US2014/030853 WO 20140317
- International Announcement: WO2014/145986 WO 20140918
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D401/04 ; A61K31/4439 ; A61K31/415 ; A61K31/4545 ; A61K31/506 ; A61K31/5377 ; C07D405/14 ; C07D231/38 ; C07D403/04 ; C07D409/14 ; A61K9/00 ; A61K31/444

Abstract:
There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.
Public/Granted literature
- US20160024047A1 MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS Public/Granted day:2016-01-28
Information query