Invention Grant
US09533978B2 Pyrimidine derivatives and their use in the treatment of cancer and further diseases
有权
嘧啶衍生物及其在治疗癌症和进一步疾病中的应用
- Patent Title: Pyrimidine derivatives and their use in the treatment of cancer and further diseases
- Patent Title (中): 嘧啶衍生物及其在治疗癌症和进一步疾病中的应用
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Application No.: US14469515Application Date: 2014-08-26
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Publication No.: US09533978B2Publication Date: 2017-01-03
- Inventor: Nicholas James Bennett , Stephen Thom , Thomas McInally
- Applicant: AstraZeneca AB
- Applicant Address: JP Osaka
- Assignee: Sumitomo Dainippon Pharma Co., Ltd
- Current Assignee: Sumitomo Dainippon Pharma Co., Ltd
- Current Assignee Address: JP Osaka
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- Main IPC: C07D413/12
- IPC: C07D413/12 ; C07D239/48 ; C07D239/49

Abstract:
The invention concerns compounds of Formula (I): wherein L1, R1, R2, R3, R4 and X are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of disease, for example cancer.
Public/Granted literature
- US20150080396A1 Novel Pyrimidine Derivatives and Their Use in the Treatment of Cancer and Further Diseases Public/Granted day:2015-03-19
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