Invention Grant
- Patent Title: Amino-derivatives as novel inhibitors of histone deacetylase
- Patent Title (中): 氨基衍生物作为组蛋白脱乙酰酶的新型抑制剂
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Application No.: US14538317Application Date: 2014-11-11
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Publication No.: US09533979B2Publication Date: 2017-01-03
- Inventor: Patrick Rene Angibaud , Kristof Van Emelen , Virginie Sophie Poncelet , Bruno Roux
- Applicant: JANSSEN PHARMACEUTICA N.V.
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agency: Baker & Hostetler LLP
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/14 ; C07D407/14 ; C07D409/14 ; C07D413/14 ; C07D417/14 ; C07D413/12 ; C07D211/14 ; C07D217/04 ; A61K31/402 ; C07D207/09 ; C07D207/14 ; C07D211/58 ; C07D213/78 ; C07D217/02 ; C07D239/42 ; C07D295/155 ; C07D295/26 ; C07D307/68 ; C07D401/04 ; C07D403/04 ; C07D409/12 ; C07D413/04 ; C07D471/04 ; C07D471/10 ; C07D513/04 ; C12Q1/48 ; A61K31/435 ; A61K31/495 ; A61K31/506 ; A61K45/06 ; A61K31/4427 ; A61K31/454 ; A61K31/5377 ; A61K31/40 ; A61K31/472 ; A61K31/496 ; C07D217/16 ; C07D405/06 ; A61K31/4545 ; C12Q1/34
Abstract:
This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20150065478A1 Amino-Derivatives As Novel Inhibitors Of Histone Deacetylase Public/Granted day:2015-03-05
Information query
