Invention Grant
- Patent Title: Ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors
- Patent Title (中): 环稠合的双环吡啶基衍生物作为FGFR4抑制剂
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Application No.: US14972984Application Date: 2015-12-17
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Publication No.: US09533988B2Publication Date: 2017-01-03
- Inventor: Nicole Buschmann , Robin Alec Fairhurst , Pascal Furet , Thomas Knöpfel , Catherine Leblanc , Lv Liao , Robert Mah , Pierre Nimsgern , Sebastien Ripoche , Jing Xiong , Bo Han , Can Wang , Xianglin Zhao
- Applicant: Nicole Buschmann , Robin Alec Fairhurst , Pascal Furet , Thomas Knöpfel , Catherine Leblanc , Lv Liao , Robert Mah , Pierre Nimsgern , Sebastien Ripoche , Jing Xiong , Bo Han , Can Wang , Xianglin Zhao
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Scott W. Reid
- Priority: WOPCT/CN2013/086003 20131025; WOPCT/CN2014/088094 20141003
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D498/04 ; C07D519/00 ; A61K31/444 ; A61K31/497 ; A61K31/506 ; A61K31/5377 ; A61K31/5383 ; A61K31/541 ; A61K31/55
Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.
Public/Granted literature
- US20160102092A1 Ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors Public/Granted day:2016-04-14
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