Invention Grant
US09534033B2 Targeted interferons demonstrating potent apoptotic and anti-tumor activities
有权
靶向干扰素表现出有力的凋亡和抗肿瘤活性
- Patent Title: Targeted interferons demonstrating potent apoptotic and anti-tumor activities
- Patent Title (中): 靶向干扰素表现出有力的凋亡和抗肿瘤活性
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Application No.: US14015838Application Date: 2013-08-30
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Publication No.: US09534033B2Publication Date: 2017-01-03
- Inventor: Sherie L. Morrison , Tzu-Hsuan Huang , Caiyun Xuan
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Weaver Austin Villeneuve & Sampson LLP
- Agent Tom Hunter
- Main IPC: A61K38/21
- IPC: A61K38/21 ; A61K47/48 ; A61K39/00 ; C07K14/56 ; C07K14/555 ; C07K16/28 ; C07K16/32 ; C07K14/565
Abstract:
Novel chimeric moieties that show significant efficacy against cancers are provided. In certain embodiments the chimeric moieties comprise a targeting moiety attached to an interferon. In certain embodiments, the chimeric moieties comprise fusion proteins where an antibody that specifically binds to a cancer marker is fused to interferon alpha (IFN-α) or interferon beta (IFN-β).
Public/Granted literature
- US20140079668A1 TARGETED INTERFERONS DEMONSTRATE POTENT APOPTOTIC AND ANTI-TUMOR ACTIVITIES Public/Granted day:2014-03-20
Information query
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