Invention Grant
US09534209B2 Methods and tools for identification of RSK/MSK kinase inhibitors
有权
用于鉴定RSK / MSK激酶抑制剂的方法和工具
- Patent Title: Methods and tools for identification of RSK/MSK kinase inhibitors
- Patent Title (中): 用于鉴定RSK / MSK激酶抑制剂的方法和工具
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Application No.: US14431008Application Date: 2013-09-30
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Publication No.: US09534209B2Publication Date: 2017-01-03
- Inventor: Jacob Lauwring Andersen , Borbala Gesser , Poul Nissen , Lars Iversen
- Applicant: Aarhus Universitet , Region Midtjylland
- Applicant Address: DK Aarhus DK Viborg
- Assignee: Aarhus Universitet,Region Midtjylland
- Current Assignee: Aarhus Universitet,Region Midtjylland
- Current Assignee Address: DK Aarhus DK Viborg
- Agency: Dinsmore & Shohl LLP
- Agent Weston Gould
- Priority: DK201270593 20120928
- International Application: PCT/DK2013/050309 WO 20130930
- International Announcement: WO2014/048442 WO 20140403
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C30B29/58 ; C30B7/00 ; C40B30/02 ; G06F19/12 ; G06F19/16 ; G06F19/00
Abstract:
The present invention concerns 3D-crystals of complexes of ribosomal S6 kinase (RSK) and mitogen- and stress-activated protein kinase (MSK) proteins and their ligands, as well as methods for crystallization, three-dimensional structure determination and structure assisted methods for identifying ligands of said proteins.
Public/Granted literature
- US20150247133A1 METHODS AND TOOLS FOR IDENTIFICATION OF RSK/MSK KINASE INHIBITORS Public/Granted day:2015-09-03
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