Invention Grant
- Patent Title: Nucleotide analogs and process for making same enzyme
- Patent Title (中): 核苷酸类似物和制备相同酶的方法
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Application No.: US14174981Application Date: 2014-02-07
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Publication No.: US09534243B2Publication Date: 2017-01-03
- Inventor: John P. Marino , Zvi Kelman , Jerard Hurwitz , Gary G. Giulian
- Applicant: John P. Marino , Zvi Kelman , Jerard Hurwitz , Gary G. Giulian
- Applicant Address: US DC Washington US NY New York US MD College Park
- Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE,MEMORIAL SLOAN KETTERING CANCER CENTER,UNIVERSITY OF MARYLAND
- Current Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE,MEMORIAL SLOAN KETTERING CANCER CENTER,UNIVERSITY OF MARYLAND
- Current Assignee Address: US DC Washington US NY New York US MD College Park
- Agent Toby D. Hain
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12P19/32 ; C07H19/10 ; C07H19/207 ; C12P19/30
Abstract:
A process for making a nucleotide analog includes combining a first substrate that includes a linker and a base with a second substrate to form a substrate composition. An enzyme contacts the substrate composition and catalyzes formation of the nucleotide analog from the first substrate and the second substrate. Additionally, a composition includes the first substrate, second substrate, the enzyme, the nucleotide analog, and optional additives.
Public/Granted literature
- US20140170711A1 NUCLEOTIDE ANALOGS AND PROCESS FOR MAKING SAME ENZYME Public/Granted day:2014-06-19
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