A safety barrier is formed of framing, including a guard rail that defines the infill below the rail without the use of pickets. The infill is covered with mesh screen, which may be made of nylon which has greater tensile strength than conventional fiberglass. The mesh screen is held to the framing by an extruded base. The base has a central channel between two flat spline grooves. Flat splines hold mesh screen in their respective grooves more securely than conventional friction-based channel splines. A metal plate is positioned in the central channel to enables screws that secure the base to be tightened to hold it to the framing better. The elimination of pickets in the infill leaves the view unobstructed and allows other treatments of that portion of a deck or porch that are more aesthetically pleasing without compromising safety.