Provided are a method and device for dynamically adjusting waiting time of uplink macro diversity combining. In the embodiments of the disclosure, in accordance with the real-time transmission condition and time delay of each link of the current macro diversity, as well as the specific time for DCH FP data frames having the same CFN from different links to arrive at an RNC, the RNC dynamically increases or reduces the waiting time of macro diversity combining, thereby improving the processing efficiency and accuracy rate of macro diversity combining.